Wai T Wong Selected Research

Retinaldehyde (Retinal)

12/2021	Intravitreous treatment of severe ocular von Hippel-Lindau disease using a combination of the VEGF inhibitor, ranibizumab and PDGF inhibitor, E10030: Results from a phase 1/2 clinical trial.
1/2019	C3- and CR3-dependent microglial clearance protects photoreceptors in retinitis pigmentosa.
1/2019	Absence of TGFβ signaling in retinal microglia induces retinal degeneration and exacerbates choroidal neovascularization.
1/2018	Microglia in the Retina: Roles in Development, Maturity, and Disease.
1/2018	Deletion of the von Hippel-Lindau Gene in Hemangioblasts Causes Hemangioblastoma-like Lesions in Murine Retina.
5/2017	Systemic Sunitinib Malate Treatment for Advanced Juxtapapillary Retinal Hemangioblastomas Associated with von Hippel-Lindau Disease.
1/2017	Photoreceptor protection via blockade of BET epigenetic readers in a murine model of inherited retinal degeneration.
1/2017	Tamoxifen Provides Structural and Functional Rescue in Murine Models of Photoreceptor Degeneration.
12/2016	LONGITUDINAL STRUCTURAL CHANGES IN LATE-ONSET RETINAL DEGENERATION.
1/2016	Aging Changes in Retinal Microglia and their Relevance to Age-related Retinal Disease.

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Wai T Wong Research Topics

Disease

16	Macular Degeneration (Age-Related Maculopathy) 01/2020 - 09/2008
9	Hemangioblastoma 12/2021 - 02/2007
8	von Hippel-Lindau Disease (von Hippel Lindau Disease) 12/2021 - 02/2007
8	Geographic Atrophy 01/2017 - 12/2010
6	Inflammation (Inflammations) 01/2021 - 05/2009
6	Retinal Diseases 01/2019 - 11/2004
5	Atrophy 01/2020 - 09/2011
5	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2019 - 09/2015
5	Neoplasms (Cancer) 01/2018 - 01/2008
4	Macular Edema 11/2018 - 05/2009
3	Choroidal Neovascularization 01/2019 - 11/2009
3	Retinal Degeneration 01/2019 - 05/2011
3	Hemorrhage 01/2018 - 03/2010
3	Glaucoma 01/2018 - 03/2014
3	Disease Progression 05/2017 - 05/2011
3	Cataract (Cataracts) 05/2015 - 05/2009
3	Eye Diseases (Eye Disease) 02/2014 - 05/2008
2	Neuroinflammatory Diseases 01/2019 - 03/2015
2	Sepsis (Septicemia) 01/2017 - 11/2016
1	Genetic Risk Score 11/2021
1	Coinfection 07/2021
1	Virus Diseases (Viral Diseases) 07/2021
1	Bacterial Infections (Bacterial Infection) 07/2021
1	Papilledema 01/2021
1	Fibrosis (Cirrhosis) 01/2018
1	Chronic Obstructive Pulmonary Disease (COPD) 10/2017
1	Eosinophilia 10/2017
1	Blindness (Hysterical Blindness) 01/2017
1	Breast Neoplasms (Breast Cancer) 01/2017
1	Neonatal Sepsis 01/2017
1	Septic Shock (Toxic Shock Syndrome) 11/2016
1	Diabetic Retinopathy (Retinopathy, Diabetic) 03/2014
1	Gliosis 03/2014
1	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2014
1	Lung Neoplasms (Lung Cancer) 02/2014
1	Hyperpigmentation 07/2012
1	Telangiectasis (Telangiectasia) 05/2012
1	Stargardt Disease 02/2012
1	Retinal Detachment (Retinal Detachments) 01/2012
1	Central Serous Chorioretinopathy 04/2011

Drug/Important Bio-Agent (IBA)

29	Retinaldehyde (Retinal)IBA 12/2021 - 02/2007
4	Ranibizumab (Lucentis)FDA Link 12/2021 - 11/2008
4	Complement System Proteins (Complement)IBA 11/2021 - 09/2011
4	Biomarkers (Surrogate Marker)IBA 01/2017 - 03/2014
3	LipidsIBA 11/2021 - 03/2015
3	Retinal Pigments (Pigments, Visual)IBA 01/2020 - 02/2012
3	Proteins (Proteins, Gene)FDA Link 01/2017 - 05/2008
3	LuteinIBA 02/2014 - 09/2008
3	ZeaxanthinsIBA 02/2014 - 09/2008
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2021 - 05/2017
2	Pharmaceutical PreparationsIBA 11/2018 - 01/2017
2	CytokinesIBA 01/2018 - 05/2009
2	Sirolimus (Rapamycin)FDA Link 12/2014 - 04/2013
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 07/2013 - 09/2008
2	LipofuscinIBA 03/2013 - 02/2012
2	Minocycline (Cyclops)FDA LinkGeneric 06/2012 - 09/2011
2	ChemokinesIBA 09/2011 - 06/2009
2	Therapeutic UsesIBA 05/2011 - 11/2004
1	Anti-Bacterial Agents (Antibiotics)IBA 07/2021
1	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 01/2020
1	SDDSIBA 01/2020
1	A-factor (Streptomyces)IBA 01/2019
1	Dextromethorphan (Racemethorphan)FDA LinkGeneric 11/2018
1	Fluorescein (Funduscein)FDA LinkGeneric 01/2018
1	Bronchodilator Agents (Bronchodilators)IBA 10/2017
1	Platelet-Derived Growth FactorIBA 05/2017
1	Sunitinib (Sutent)FDA Link 05/2017
1	Antimicrobial Cationic PeptidesIBA 01/2017
1	Selective Estrogen Receptor Modulators (SERM)IBA 01/2017
1	Neuroprotective AgentsIBA 01/2017
1	CathelicidinsIBA 01/2017
1	Tamoxifen FDA LinkGeneric 01/2017
1	HepcidinsIBA 01/2017
1	Peptides (Polypeptides)IBA 01/2017
1	DefensinsIBA 01/2017
1	Circular RNAIBA 11/2016
1	Long Noncoding RNAIBA 11/2016
1	MicroRNAs (MicroRNA)IBA 11/2016
1	7-ketocholesterolIBA 03/2015
1	matrigelIBA 03/2015
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 08/2014
1	beta Carotene (Betacarotene)FDA Link 02/2014
1	Vitamin E FDA LinkGeneric 02/2014
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 02/2014
1	ZincIBA 02/2014
1	CopperIBA 02/2014
1	Immunosuppressive Agents (Immunosuppressants)IBA 04/2013
1	Melanins (Melanin)IBA 02/2012
1	4-O-carboxymethylascochlorinIBA 09/2011
1	Naloxone (Narcan)FDA LinkGeneric 05/2011
1	Dihydrotestosterone (Androstanolone)IBA 04/2011
1	Finasteride (Propecia)FDA LinkGeneric 04/2011
1	AntioxidantsIBA 12/2010

Therapy/Procedure

7	Therapeutics 10/2017 - 05/2008
3	Lasers (Laser) 12/2021 - 09/2015
1	Light Coagulation 12/2021
1	Electrodes (Electrode) 01/2021
1	Length of Stay 10/2017
1	Transplantation 03/2015
1	Topical Administration 12/2010